Lung Transplant Allocation System Challenges for Pulmonary Arterial Hypertension (PAH) Patients, Letter to the Editor, Transplant International, October 28, 2025

Pulmonary arterial hypertension patients face unique challenges in lung transplantation. Unlike patients with other lung diseases, they often have relatively normal lung function tests but are in critical condition due to heart failure. This means they receive low priority scores in the standard Lung Allocation Score (LAS) system, which was designed primarily for patients with […]

Lung Transplant Allocation System Challenges for Pulmonary Arterial Hypertension (PAH) Patients, Letter to the Editor, Transplant International, October 28, 2025 Read Post »

Latest edition on the Council of Europe’s European Directorate for the Quality of Medicines and HealthCare (EDQM) Newsletter Transplant 2025 is now available

The Council of Europe’s EDQM (European Directorate for the Quality of Medicines and HealthCare) Newsletter Transplant provides regular updates on transplantation-related developments across Europe. It covers policy, regulation, quality standards, and best practices related to organ donation, allocation, and transplant safety, ensuring harmonisation across European Union member states. Additionally, the newsletter shares news on scientific

Latest edition on the Council of Europe’s European Directorate for the Quality of Medicines and HealthCare (EDQM) Newsletter Transplant 2025 is now available Read Post »

Study provides proof-of-concept that fully automated, algorithm-driven tacrolimus dosing can improve therapeutic drug monitoring in real-world clinical practice, Clinical Pharmacology and Therapeutics, October 11, 2025

Tacrolimus therapeutic drug monitoring is challenging due to high inter- and intra-patient variability. A prospective randomized controlled trial was conducted by researchers at the University Hospital in Leuven, Belgium, on 293 de novo kidney transplant recipients during the first 14 days post-transplant. A fully automated Model-informed precision dosing (MIPD) application (1) was integrated into the

Study provides proof-of-concept that fully automated, algorithm-driven tacrolimus dosing can improve therapeutic drug monitoring in real-world clinical practice, Clinical Pharmacology and Therapeutics, October 11, 2025 Read Post »

Extracorporeal Photopheresis: Emerging Role in Transplantation and Beyond, Transplantation Direct, September 2025

A newly published review in Transplantation Direct explores the growing significance ofextracorporeal photopheresis (ECP), a therapy that modulates immune responses usingpatients’ own treated blood cells. The article, authored by Panagiotis Parsonidis, MSc, and Prof. Thomas Wekerle of the Medical University of Vienna, Austria, highlights extracorporeal photopheresis’s established safety record while pointing to future opportunities for

Extracorporeal Photopheresis: Emerging Role in Transplantation and Beyond, Transplantation Direct, September 2025 Read Post »

Alveolar Septal Width as a Predictor of Chronic Lung Allograft Dysfunction and Survival After Lung Transplantation, Journal of Clinical Medicine, September 9, 2025

Researchers may have found a way to predict which lung transplant patients will develop serious complications before symptoms appear. In a study titled “Increase in Alveolar Septal Width Is a Histological Predictor of Chronic Lung Allograft Dysfunction and Survival in Lung Transplant Recipients—A Longitudinal Study” the authors measure the thickness of air sac walls in lung

Alveolar Septal Width as a Predictor of Chronic Lung Allograft Dysfunction and Survival After Lung Transplantation, Journal of Clinical Medicine, September 9, 2025 Read Post »

Understanding Risk Assessment in Pulmonary Arterial Hypertension, International Society for Heart and Lung Transplant ISHLT Consensus Statement, The Journal of Heart and Lung Transplantation – September 05, 2025

What is pulmonary arterial hypertension and why does risk assessment matter? Pulmonary arterial hypertension is a rare, serious disease where the blood vessels in thelungs become too narrow. This makes the right side of the heart work harder, which overtime can lead to heart failure. Because it can progress quickly, doctors use risk assessment (sometimes

Understanding Risk Assessment in Pulmonary Arterial Hypertension, International Society for Heart and Lung Transplant ISHLT Consensus Statement, The Journal of Heart and Lung Transplantation – September 05, 2025 Read Post »

First robotic lung transplant in Abu Dhabi, UAE, Gulf Today, July 8, 2025

Cleveland Clinic Abu Dhabi has achieved a historic milestone by performing the Gulf region’s first robotic lung transplants, making it one of only five centers worldwide to successfully complete this advanced procedure. Two patients with idiopathic pulmonary fibrosis and secondary pulmonary hypertension have undergone the surgery. These surgeries were quite complex due to pulmonary hypertension,

First robotic lung transplant in Abu Dhabi, UAE, Gulf Today, July 8, 2025 Read Post »

The Pulmonary Hypertension Global Patient Survey: understanding the experiences and perspectives of patients, European Respiratory Journal Open Research 2025

The key findings from the Pulmonary Hypertension Global Patient Survey (PHGPS) adult cohort of 3,329 patients have been published in the ERJ Open Research 2025, highlighting the achievements, shortcomings & regional disparities of clinical care & research globally. The Pulmonary Hypertension Global Patient Survey represents the most extensive survey of its type in the pulmonary

The Pulmonary Hypertension Global Patient Survey: understanding the experiences and perspectives of patients, European Respiratory Journal Open Research 2025 Read Post »

The landscape of referrals for lung transplantation in pulmonary arterial hypertension: a report from the Pulmonary Hypertension Association Registry, Journal of Heart and Lung Transplantation, June 26, 2025

A large US registry study of 1,671 patients with pulmonary arterial hypertension (PAH) over 4607 person-years of follow up found that lung transplant referrals are occurring far too infrequently and too late in the disease course. Despite professional society recommendations for early referral, only 12% of patients were referred for transplantation over the study period.

The landscape of referrals for lung transplantation in pulmonary arterial hypertension: a report from the Pulmonary Hypertension Association Registry, Journal of Heart and Lung Transplantation, June 26, 2025 Read Post »

Lung Transplantation Updates: Broader Indications with a Focus on Pulmonary arterial Hypertension, Zentralblatt für Chirurgie, May 15, 2025.

In their recent open-access article for the Zentralblatt für Chirurgie, Drs.: Szofia Kovacs, Alberto Benazzo, and Peter Jaksch review the latest International Society for Lung and Heart Transplantion (ISHLT) guidelines on lung transplantation, highlighting a major shift toward personalized, inclusive care. Beyond the underlying lung disease, transplant decisions now consider age, frailty, comorbidities, and psychosocial

Lung Transplantation Updates: Broader Indications with a Focus on Pulmonary arterial Hypertension, Zentralblatt für Chirurgie, May 15, 2025. Read Post »

Timing Matters: When Should Pulmonary Arterial Hypertension Patients Be Referred for Lung Transplantation? Current Opinion in Pulmonary Medicine, July 1 2025 edition

Early referral for lung transplantation can be life-saving for people with pulmonary arterial hypertension (PAH). In this important review, van der Ploeg et al. explore when and how patients across major respiratory diseases especially Pulmonary Arterial Hypertension should be referred for transplant evaluation. As medical therapies continue to improve, the urgency and timing of referral

Timing Matters: When Should Pulmonary Arterial Hypertension Patients Be Referred for Lung Transplantation? Current Opinion in Pulmonary Medicine, July 1 2025 edition Read Post »

Expert Consensus on Lung Transplantation for Pulmonary Arterial Hypertension Patients, Pulmonary Circulation, April 23, 2025

Globally, over 4,500 lung transplants are performed annually. Pulmonary Arterial Hypertension represents a unique transplantation indication because: Given these specific challenges, the authors developed guidelines for managing Pulmonary Arterial Hypertension patients who are lung transplant candidates through a modified Delphi study. The expert panel reached unanimous consensus on several key aspects of lung transplantation for

Expert Consensus on Lung Transplantation for Pulmonary Arterial Hypertension Patients, Pulmonary Circulation, April 23, 2025 Read Post »

Tacrolimus versus cyclosporine immunosuppression in lung transplantation: a systematic review and meta-analysis, BMJ Open Respiratory Research, April 2025

A systematic review and meta-analysis to determine whether tacrolimus or cyclosporine is more effective at reducing chronic lung allograft dysfunction (CLAD) in lung transplant patients was publshed on the British Medical Journal in April 2025. The researchers analyzed 4 randomized trials involving 662 patients with a mean age of 45-55 years, mostly with Chronic Obstructive

Tacrolimus versus cyclosporine immunosuppression in lung transplantation: a systematic review and meta-analysis, BMJ Open Respiratory Research, April 2025 Read Post »

Societal Costs Associated With Pulmonary Arterial Hypertension Subgroups: A Study Utilizing Linked National Registries, Pulmonary Circulation, April 17, 2025

Pulmonary arterial hypertension (PAH) represents a significant economic burden on society, as revealed by a comprehensive Swedish study published on Pulmonary Circulation on April 17, 2025, examining the societal costs associated with this condition. The research tracked patients across various pulmonary arterial hypertension subgroups—idiopathic/hereditary pulmonary arterial hypertension, pulmonary arterial hypertension associated with connective tissue disease,

Societal Costs Associated With Pulmonary Arterial Hypertension Subgroups: A Study Utilizing Linked National Registries, Pulmonary Circulation, April 17, 2025 Read Post »

The Aeson Total Artificial Heart helps three heart failure patients with pulmonary hypertension become heart transplant-eligible, The Journal of Heart and Lung Transplantation, February 5, 2025

Three heart failure patients with pulmonary hypertension (WHO Group II) became eligible for heart transplants after receiving the Aeson Total Artificial Heart, which effectively took place after 243, 155 and 109 days respectively. This innovative device, implanted with the help of the advanced Carmat system, replaces the heart’s ventricles and maintains continuous blood circulation, stabilizing

The Aeson Total Artificial Heart helps three heart failure patients with pulmonary hypertension become heart transplant-eligible, The Journal of Heart and Lung Transplantation, February 5, 2025 Read Post »

The US Food and Drug Administration (FDA) has approved clinical trials to transplant organs from genetically modified pigs into people with kidney failure

The US Food and Drug Administration (FDA) has approved pioneering clinical trials by two biotech firms to evaluate the transplantation of kidneys from genetically engineered pigs into human patients with renal failure. This breakthrough authorization could mark a significant step toward addressing the chronic shortage of human organs for transplant. Until now, such transplants were

The US Food and Drug Administration (FDA) has approved clinical trials to transplant organs from genetically modified pigs into people with kidney failure Read Post »

Proud to celebrate the 14 live webinars we have organised since the series launched in June 2023! A huge thank you to all our speakers and participants!

The Alliance for Pulmonary Hypertension (AfPH) recently concluded its 14th webinar, marking the culmination of an educational initiative that began in June 2023. These virtual gatherings brought together internationally renowned experts in pulmonary hypertension, who shared their expertise on a comprehensive range of topics crucial to advancing patient care and quality of life. The diverse

Proud to celebrate the 14 live webinars we have organised since the series launched in June 2023! A huge thank you to all our speakers and participants! Read Post »

Special issue of “Transplant International” addresses race, gender, socioeconomic and geographic disparities in transplantation

Transplant International has published a special issue of its journal on “Diversity, Equity, and Inclusion in Transplantation”. This issue presents a collection of studies that examine inequities in transplantation related to race, gender, socioeconomics, and geography, providing evidence and insights into these persistent disparities. Download the pdf of the special issue of Transplant International at

Special issue of “Transplant International” addresses race, gender, socioeconomic and geographic disparities in transplantation Read Post »

Full transcript of the PVRI live webinar on “Debunking myths about Lung Transplantation”, September 25, 2024, now available and translatable in 50 languages!

The Pulmonary Vascular Research Institute (PVRI) organised a patient-directed webinar on “Debunking Myths of Lung Transplantation” on September 25, 2024. This was an outstanding webinar: the explanations were exceptionally clear and delivered in easy-to-understand language, covering every step of the transplant journey—from getting listed and preparing for surgery, through the operation and immediate post-op, to

Full transcript of the PVRI live webinar on “Debunking myths about Lung Transplantation”, September 25, 2024, now available and translatable in 50 languages! Read Post »

Patient centered care at the heart of The Transplantation Society’s Annual Congress in Istanbul, 22-25 September 2024

The 30th The Transplantation Society (TTS) Annual Congress in Istanbul brought together over 2.500 transplant professionals from 90 countries, with a further 500 attending remotely. It began with a memorable opening ceremony, attended by prominent figures such as the Minister of Health, the Governor, and the Mayor of Istanbul. The ceremony featured a compelling speech

Patient centered care at the heart of The Transplantation Society’s Annual Congress in Istanbul, 22-25 September 2024 Read Post »

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