This month’s news roundup brings together the latest in pulmonary hypertension research and care. On the clinical front, several new studies stand out — from encouraging long-term rehabilitation data in the FONCE-HTAP trial, to new insights into pulmonary artery stiffness, BMPR2 signalling, and exercise safety after pulmonary endarterectomy. On the drug development side, we cover regulatory and trial updates. Beyond the science, you’ll find webinar recordings, community fundraising efforts, and a look at some of medicine’s most surprising accidental discoveries. As always, our thanks go to the researchers, clinicians, and patient advocates whose invaluable work keeps this field moving forward.
Clinical research & trial results
- FONCE-HTAP rehabilitation trial (Annals of American Thoracic Society (ATS)
- GoDeep meta-registry on pulmonary artery stiffness (CHEST)
- BMPR2 signalling across pulmonary hypertension subgroups (ERJ Open Research)
- Exercise safety after pulmonary endarterectomy (ERJ Open Research)
- Inhaled pulmonary vasodilators, perioperative use (Journal of Heart and Lung Transplant)
- Sleep difficulties, anxiety, depression and QoL in pulmonary hypertension (Clinical Respiratory Journal)
Drug development & regulatory news
- US Food and Drug Administration (FDA) accepts New Drug Application (NDA) for ralinepag (United Therapeutics)
- Tenax Therapeutics Phase 3 LEVEL trial (TNX-103, PH-HFpEF)
- Insmed 12-month OLE data for TPIP
Organ donation and transplant
- World Health Organisation (WHO) public consultation on organ donation/transplant strategy
- Early referral for lung transplantation (CHEST webinar recording)
Webinars
- “Co-creating care: patients as equal partners” (ERS webinar)
Patient community, advocacy & fundraising
- New EMPHASIS magazine issue (PHA UK)
- Krishma Kaur’s Kilimanjaro climb for PHA UK and Alzheimer’s Society
General interest
- “From Warfarin to Viagra” — accidental medical discoveries