A study published in Pulmonary Circulation on June 17, 2025 has examined the relationships between fatigue, pain, anxiety, depression, and quality of life in 68 adults with pulmonary hypertension, recruited from global pulmonary hypertensions associations, who completed a series of self-report measures. The researchers found alarmingly high rates of these symptoms: 86.8% experienced clinical levels of fatigue, 73.5% had depression, and 58.8% had anxiety, while only 22.1% felt confident managing their pain.
The researchers concluded that these symptoms require holistic, multimodal treatment approaches rather than addressing them individually. They emphasized the need to screen all pulmonary hypertension patients for these interconnected symptoms regardless of demographics, as none of the demographic factors predicted symptom severity. The findings support integrated care targeting fatigue, pain, anxiety, and depression together to improve overall quality of life in pulmonary hypertension patients.
Read more at this link on Wiley Online Library
Citation
Rawlings, G.H., Stark, A., Armstrong, I., Costin, V. and Thompson, A.R. (2025), The Role of Psychological Distress on Health-Related Quality of Life, Fatigue, and Pain in Adults With Pulmonary Hypertension. Pulmonary Circulation, 15: e70101. https://doi.org/10.1002/pul2.70101
