Prognostic relevance of exercise pulmonary hypertension: results of the multicentre PEX-NET Clinical Research Collaboration, European Respiratory Journal

The PEX-NET (Pulmonary Haemodynamics during Exercise Network) registry enrolled patients who underwent clinically indicated right heart catheterisations both at rest and ergometer exercise from 23 PH centres worldwide. Its objective was to explore the prognostic relevance of exercise haemodynamics and its added value to resting haemodynamics. The study found that exercise pulmonary hypertension measures may independently predict survival in patients with normal or mildly elevated pulmonary arterial pressure.

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Citation

Prognostic relevance of exercise pulmonary hypertension: results of the multicentre PEX-NET Clinical Research Collaboration, Gabor Kovacs, Marc Humbert, Alexander Avian, Gregory D. Lewis, Silvia Ulrich, Anton Vonk Noordegraaf, Rogerio Souza, Nazzareno Galiè, Rajeev Malhotra, Stephanie Saxer, Ekkehard Grünig, Benjamin Egenlauf, Ralf Ewert, Alexander Heine, Ryan J. Tedford, Brian A. Houston, Krzysztof Kasperowicz, Marcin Kurzyna, Stephan Rosenkranz, Simon Herkenrath, Joan Albert Barbera, Isabel Blanco, Rudolf K.F. Oliveira, Mads Andersen, Laurent Savale, David Systrom, Bradley A. Maron, Khodr Tello, Robin Condliffe, Susanna Mak, Claudia Baratto, Steven Hsu, Michele D’Alto, Colm McCabe, Philippe Herve, Horst Olschewski, European Respiratory Journal 2024 64(6): 2400698; DOI: https://doi.org/10.1183/13993003.00698-2024

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