A new pre-clinical study shows that stem cell-derived conditioned medium (iPSC-CM)—the liquid remaining after stem cells are cultured—reduces signs of pulmonary arterial hypertension in rat and cell models. In pulmonary arterial hypertension rats treated with daily iPSC-CM infusions, researchers observed reduced blood pressure in the right ventricle, decreased heart enlargement, and thinner pulmonary arterial walls. […]

A recent study titled “Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes” analysed two common health factors in people with pulmonary hypertension: inflammation and body weight. Inflammation is associated with all types of pulmonary hypertension. In the study inflammation was measured by a blood test called C-reactive protein (CRP), and body

In pulmonary arterial hypertension (PAH) lung blood vessel cells grow excessively, increasing vascular resistance and ultimately leading to right heart failure. While researchers understand many molecular mechanisms behind pulmonary arterial hypertension, effective treatments remain limited. Programmed cell death (PCD) plays a crucial role in the pathogenesis of various diseases, including cancer, chronic conditions, cardiovascular disorders,