The findings of a prospective study on 93 patients (66% women, 75% PAH, 25% CTEPH, 57±17 years), all on pulmonary hypertension-targeted oral medication, between 2013 and 2023, were recently published in the British Medical Journal Open Respiratory Research. These reveal that mean MPR (Medication Possession Ratio) and self-reported adherence were overall high, with 78% of patients classified as adherent. Adherent patients improved clinical outcomes, contrary to non-adherent patients. The authors recommend that regular assessment of adherence should be incorporated into clinical practice, especially for patients who fail to show improvement after initiating therapy. Particular attention should be paid to younger patients and those experiencing adverse effects, as they may require additional support to maintain proper adherence.
Read more at this link on the NIH National Library of Medicine
Citation
Reimann L, Preiss H, Müller J, Huber P, Mayer L, Langleben D, Ulrich S, Lichtblau M. Medication adherence and clinical outcome in patients with pulmonary arterial hypertension or distal chronic thromboembolic pulmonary hypertension. BMJ Open Respir Res. 2025 Apr 5;12(1):e003023. doi: 10.1136/bmjresp-2024-003023. PMID: 40187745.
