This is a small study but it addresses a very important but often overlooked issue, that of injection site pain for pulmonary arterial hypertension patients being treated with sub-cutaneous treprostinil, which can significantly affect quality of life. The researchers found that topical 10% lidocaine gel provided rapid and effective relief of injection site pain, facilitating continuation of therapy without pain-related interruption.
Read more at this link on Springer Nature
Citation
Kawamoto, S., Miyao, M., Sakurai, K. et al. Efficacy of 10% lidocaine gel for injection site pain associated with treprostinil in the treatment of pulmonary hypertension: a report of four cases. JA Clin Rep (2025). https://doi.org/10.1186/s40981-025-00834-4
See also
Our article oabout a new investigational mode of delivery of treprostinil via a skin patch at this link
