The aim of the SPHERe study is to test the clinical and cost-effectiveness of a supervised exercise rehabilitation intervention with psychosocial support compared to best practice usual care for people with pulmonary hypertension in the community/outpatient setting.
The SPHERe study is the first multi-centre clinical randomised controlled trial (RCT) to assess the clinical and cost effectiveness of a supervised exercise rehabilitation intervention compared to usual care, delivered in the UK National Health Service (NHS, for people in all PH groups. Results will inform clinicians and commissioners as to whether or not supervised exercise rehabilitation is effective and should be routinely provided for people with PH.
This study is funded by the UK National Institute for Health Research (NIHR) HTA programme (project number17/129/02).
Read more about the SPHERe trial on the website of the Warwick Clinical Trials Unit at this link
Citation
McGregor G, Bruce J, Ennis S, Mason J, Lall R, Ji C, Sandhu H, Seers K, Banerjee P, Canaway A, Booth K, Taylor SJC, Robertson E, Pincus T, Singh S, Fitzmaurice D, Bowater S, Clift P, Underwood M. Supervised pulmonary hypertension exercise rehabilitation (SPHERe): study protocol for a multi-centre randomised controlled trial. BMC Pulm Med. 2020 May 19;20(1):143. doi: 10.1186/s12890-020-01182-y. PMID: 32429969; PMCID: PMC7236437.