A study published in Pulmonary Circulation and reported in the March 11 issue of Pulmonary Hypertension News, has found that higher blood levels of immunoglobulin E (IgE) — an immune molecule normally associated with allergies — are linked to worse right heart function in pulmonary arterial hypertension patients. Those with elevated IgE levels showed more severe symptoms, greater limitations in physical activity, and signs of the right ventricle struggling to pump blood into the lungs. The findings suggest that the immune system may play a role in accelerating heart failure in pulmonary arterial hypertension, and the authors propose IgE as a potential diagnostic biomarker, with anti-IgE therapy as a possible avenue for future treatment.
Read more at this link on Pulmonary Hypertension News
The original article titled “Association of Immunoglobulin E With Right Ventricular Dysfunction in Pulmonary Arterial Hypertension” can be found here