In a recent LinkedIn post Prof. Werner Seeger writes that the GoDeep meta-registry analysis about the predictive power of pulmonary artery stiffness – right ventricular interplay in mild pulmonary hypertension (PH) is now online. He reports that in the analysis, notably, parameters integrating pulsatile vascular load and interdependent right ventricular function possess predictive power independent of pulmonary vascular resistance/total vascular resistance across the full spectrum of pulmonary hypertension. Moreover, they allow meaningful risk stratification in mild pulmonary hypertension patients, where conventional parameters lack discriminative prognostic power.
Read more at this link on CHEST
Read more about the Pulmonary Vascular Research Institute GoDeep meta-registry here
Citation
Yogeswaran A, Fünderich M, Kiely DG, Annis JS, Brittain E, Bogaard HJ, Balasubramanian A, Hassoun PM, Howard L, Lawrie A, Wilkins MR, Thenappan T, Elwing J, Jose A, Lichtblau M, Ulrich S, Harbaum L, Klose H, Sweatt AJ, Zamanian RT, Lau EM, Kuronuma K, Matsubara H, Dwyer N, Sirenko Y, Torbas O, Eichstaedt CA, Grünig E, Lavender M, Arvanitaki A, Giannakoulas G, Frauendorf M, Williams PG, Zhai Z, Zhang Z, Anthi A, Dima E, Sabbour H, Saleh K, Ghio S, Scelsi L, De Luque Figueroa J, Orozco-Levi M, Ramirez-Sarmiento A, Sivakumaran S, Anderson J, Chan SY, King I, Olschewski H, Ghofrani HA, Grimminger F, Majeed RW, Wilhelm J, Tello K, Seeger W. Predictive Power of Pulmonary Artery Stiffness – Right Ventricular Interplay, but not Pulmonary Vascular Resistance, in Mild Pulmonary Hypertension: A PVRI GoDeep meta-registry analysis. Chest. 2026 Aug 26:S0012-3692(26)06476-7. doi: 10.1016/j.chest.2026.07.5243. Epub ahead of print. PMID: 42648467.
